Research report from NORD grant
Posted: Wed Jun 22, 2016 4:47 pm
A new research paper:
Orthostatic tremor: a cerebellar pathology?
“Functional connectivity between the lateral cerebellum and the supplementary motor area was abnormally increased in patients with orthostatic tremor, and correlated positively with tremor severity. After repetitive transcranial stimulation, tremor severity and functional connectivity between the lateral cerebellum and the supplementary motor area were reduced. We provide an explanation for orthostatic tremor pathophysiology, and demonstrate the functional relevance of cerebello-thalamo-cortical connections in tremor related to cerebellar defects.”
This research was in part financed by the OT community through the NORD OT Research grant. Thank you to the researchers for studying this rare disease and to those who participated in the NORD OT fund!
(and thank you to margie1627 for sending me this link)
Orthostatic tremor: a cerebellar pathology?
Cécile Gallea, Traian Popa, Daniel García-Lorenzo, Romain Valabregue, André-Pierre Legrand, Emmanuelle Apartis, Lea Marais, Bertrand Degos, Cecile Hubsch, Sara Fernández-Vidal, Eric Bardinet, Emmanuel Roze, Stéphane Lehéricy, Sabine Meunier, Marie Vidailhet
DOI: http://dx.doi.org/10.1093/brain/aww140 aww140 First published online: 21 June 2016
Link to online article - http://bit.ly/OTbrainresearch
you can also find the PDF of the research paper here - http://bit.ly/OTbrainresearchPDF
Orthostatic tremor: a cerebellar pathology?
“Functional connectivity between the lateral cerebellum and the supplementary motor area was abnormally increased in patients with orthostatic tremor, and correlated positively with tremor severity. After repetitive transcranial stimulation, tremor severity and functional connectivity between the lateral cerebellum and the supplementary motor area were reduced. We provide an explanation for orthostatic tremor pathophysiology, and demonstrate the functional relevance of cerebello-thalamo-cortical connections in tremor related to cerebellar defects.”
This research was in part financed by the OT community through the NORD OT Research grant. Thank you to the researchers for studying this rare disease and to those who participated in the NORD OT fund!
(and thank you to margie1627 for sending me this link)
Orthostatic tremor: a cerebellar pathology?
Cécile Gallea, Traian Popa, Daniel García-Lorenzo, Romain Valabregue, André-Pierre Legrand, Emmanuelle Apartis, Lea Marais, Bertrand Degos, Cecile Hubsch, Sara Fernández-Vidal, Eric Bardinet, Emmanuel Roze, Stéphane Lehéricy, Sabine Meunier, Marie Vidailhet
DOI: http://dx.doi.org/10.1093/brain/aww140 aww140 First published online: 21 June 2016
Link to online article - http://bit.ly/OTbrainresearch
you can also find the PDF of the research paper here - http://bit.ly/OTbrainresearchPDF