Resting state functional MRI reveals abnormal network connectivity in orthostatic tremor

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Resting state functional MRI reveals abnormal network connectivity in orthostatic tremor

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A new research report on OT -

Title : Resting state functional MRI reveals abnormal network connectivity in orthostatic tremor

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In this study the researchers at the University Hospital in Madrid, studied the response of 14 OT patients in a resting state -

“Patients and controls were positioned in the scanner and were told to relax with their eyes closed. They were immobilized with a custom-fit blue bag vacuum mold (Medical Intelligence, Schwabmünchen, Germany) to prevent motion artifacts. Earplugs and noise-reduction headphones were used to attenuate scanner noise. The functional run required 6 minutes to complete.”….

“In summary, in this exploratory study, we observed selective impairments of RSNs intrinsic functional connectivity in OT patients. This and other future resting-state fMRI studies might provide a novel method to understand the pathophysiological mechanisms of motor and nonmotor features of OT.”

LINK TO ARTICLE

July 2016 - Volume 95 - Issue 29 - p e4310
doi: 10.1097/MD.0000000000004310
Research Article: Observational Study
Resting state functional MRI reveals abnormal network connectivity in orthostatic tremor

Benito-León, Julián MD, PhD; Louis, Elan D. MD, MSc; Manzanedo, Eva PhD; Hernández-Tamames, Juan Antonio PhD; Álvarez-Linera, Juan MD, PhD; Molina-Arjona, José Antonio MD, PhD; Matarazzo, Michele MD; Romero, Juan Pablo MD, PhD; Domínguez-González, Cristina MD; Domingo-Santos, Ángela MD; Sánchez-Ferro, Álvaro MD
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